Dynamic contrast-enhanced breast MRI features correlate with invasive breast cancer angiogenesis

Dynamic NMR effects in breast cancer dynamic-contrast-enhanced MRI.

The passage of a vascular-injected paramagnetic contrast reagent (CR) bolus through a region-of-interest affects tissue (1)H(2)O relaxation and thus MR image intensity. For longitudinal relaxation [R(1) identical with (T(1))(-1)], the CR must have transient molecular interactions with water. Because the CR and water molecules are never uniformly distributed in the histological-scale tissue comp...

Study of lymph nodes with dynamic contrast-enhanced breast MRI

Measurement of pharmacokinetic parameters in histologically graded invasive breast tumours using dynamic contrast-enhanced MRI.

Dynamic contrast-enhanced MRI (DCE-MRI) has demonstrated high sensitivity for detection of breast cancer. Analysis of correlation between quantitative DCE-MRI findings and prognostic factors (such as histological tumour grade) is important for defining the role of this technique in the diagnosis of breast cancer as well as the monitoring of neoadjuvant therapies. This paper presents a practical...

Differentiation of Breast Cancer from Fibroadenoma with Dual-Echo Dynamic Contrast-Enhanced MRI

Dynamic contrast-enhanced magnetic resonance imaging (DCE MRI) of the breast is a routinely used imaging method which is highly sensitive for detecting breast malignancy. Specificity, though, remains suboptimal. Dynamic susceptibility contrast magnetic resonance imaging (DSC MRI), an alternative dynamic contrast imaging technique, evaluates perfusion-related parameters unique from DCE MRI. Prev...

significance of additional non-mass enhancement in patients with breast cancer on preoperative 3t dynamic contrast enhanced mri of the breast

conclusion the possibility of malignancy is strongly indicated when additional nme lesions show linear or segmental enhancement on preoperative 3t dce-mri in patients with recently diagnosed breast cancer. results on histopathologic analysis of the 88 nme lesions, 73 (83%) were malignant and 15 (17%) were benign. lesion size did not differ significantly between malignant and benign lesions (p =...